In silico systems analysis of biopathways
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چکیده
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منابع مشابه
Biopathways representation and simulation on hybrid functional Petri net
The following two matters should be resolved in order for biosimulation tools to be accepted by users in biology/medicine: (1) remove issues which are irrelevant to biological importance, and (2) allow users to represent biopathways intuitively and understand/manage easily the details of representation and simulation mechanism. From these criteria, we firstly define a novel notion of Petri net ...
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Biopathway databases have been developed, such as KEGG and EcoCyc, that compile interaction structures of biopathways together with biological annotations. However, these biopathways are not directly editable and simulatable. Thus, we have made an application, the Biopathway Executer (BPE), that reconstructs these two major biopathway databases to XML formats of modeling and simulation platform...
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In the post-genome era, biopathway information processing is one of the most important research topics in Bioinformatics. From a biochemical and biomedical viewpoint, research progress will be very beneficial to human beings, e.g. developments of medicine manufacture and effective medical treatment for each patient. Thus, this thesis discusses the importance of a biopathway development environm...
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Background & Objective: A main contest in chemotherapy is to obtain regulator above the biodistribution of cytotoxic drugs. The utmost promising strategy comprises of drugs coupled with a tumor-targeting bearer that results in wide cytotoxic activity and particular delivery. The B-subunit of Shiga toxin (STxB) is nontoxic and possesses low immunogenicity that exactly binds to t...
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The 5th BioPathways Consortium Meeting gathered 21 speakers, close to 100 registered participants and an undetermined number of visitors from neighbouring SIGs. The meeting featured two main scientific sessions, focusing respectively on ‘Regulation and Interactions on a Systems Scale’ and ‘Function and Evolution of Metabolic Networks’, an ‘Ontologies, Databases and Data Integration’ session, an...
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